Search results
Results from the WOW.Com Content Network
The total volume of the hippocampus is also reduced. [2] The reduced volume arises from neuronal cell loss, and increased signal arises from gliosis. [2] The 18F-fluorodeoxyglucose PET (18F-FDG) scan may show decreased glucose metabolism in the temporal lobe with hippocampal atrophy. [2]
Cerebral atrophy can be hard to distinguish from hydrocephalus because both cerebral atrophy and hydrocephalus involve an increase in cerebrospinal fluid (CSF) volume. In cerebral atrophy, this increase in CSF volume comes as a result of the decrease in cortical volume. In hydrocephalus, the increase in volume happens due to the CSF itself. [20]
Individuals afflicted suffer unilateral volume loss, as evidenced by MRI scans. [9] Hippocampal sclerosis involves neural loss and a selective mesial temporal sclerosis (MTS) danger and is likely caused by an overactivation of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors by the surplus ...
encouraging weight loss in people with obesity. ... hippocampal volume, and total brain volume. The researchers controlled for sociodemographic factors, such as age, sex, and education level ...
The treatment with steroids was stopped and three years later (while still taking buspirone, albuterol, fluticasone and salmeterol inhalers, loratadine and theophylline) the boy showed gradual improvement, but MRI brain scans revealed that the patient's hippocampal volume was 19.5% smaller than that of his twin.
Hippocampal volume is the first imaging biomarker to be qualified, with the help of ADNI data, by the European Medicines Agency to select patients for clinical trials. [42] ADNI also contributed to the development of a standardized technique to manually measure hippocampal volume from MRI scans for use in clinical trials. [43] APOE ε4 allele.
[16] One study found "subtle hippocampal volume loss" in patients with TEA, but the atrophy did not correspond to measures of either ALF or autobiographical memory loss, suggesting "a more diffuse physiological basis rather than being a consequence of structural damage." [14] Anticonvulsant medication; Antiepileptic drugs sometimes affect memory.
The hallmark symptom of LATE is a progressive memory loss that predominantly affects short-term and episodic memory. [1] This impairment is often severe enough to interfere with daily functioning and usually remains the chief neurologic deficit, unlike other types of dementia in which non-memory cognitive domains and behavioral changes might be noted earlier or more prominently. [1]