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Most people recover within a week or so. In about 5% of cases, symptoms worsen and can become life-threatening. This is called severe dengue (formerly called dengue hemorrhagic fever or dengue shock syndrome). [21] [23] Severe dengue can lead to shock, internal bleeding, organ failure and even death. [24]
A pill for dengue fever developed by Johnson & Johnson appeared to protect against a form of the virus in a handful of patients in a small human challenge trial in the United States, according to ...
Dengue vaccine is a vaccine used to prevent dengue fever in humans. [9] Development of dengue vaccines began in the 1920s but was hindered by the need to create immunity against all four dengue serotypes. [10] As of 2023, there are two commercially available vaccines, sold under the brand names Dengvaxia and Qdenga. [11] [12]
Dengue fever is usually not fatal, but infection with one of four serotypes can increase later susceptibility to other serotypes, resulting in a potentially fatal disease called severe dengue. [40] Dengue fever is caused by a flavivirus which is spread mostly by the bite of the Aedes aegypti mosquito. [40] No treatment for either dengue or ...
A new vaccine candidate was more than 83 percent effective at protecting against hospitalizations over a three-year clinical trial. Dengue virus is a mosquito-borne disease that can cause severe ...
Most dengue fever patients recover in a week, but in severe cases the disease can be life-threatening and require hospitalization since it can result in shock, internal bleeding and even death.
Treatment of acute dengue is supportive, using either oral or intravenous rehydration for mild or moderate disease, and intravenous fluids and blood transfusion for more severe cases. The incidence of dengue fever has increased dramatically since the 1960s, with around 50–100 million people infected yearly. Early descriptions of the condition ...
Balapiravir (R-1626, Ro4588161) is an experimental antiviral drug which acts as a polymerase inhibitor.There were efforts to develop it as a potential treatment for hepatitis C, and it was subsequently also studied in Dengue fever, but was not found to be useful.
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