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Steve Horvath is a German–American aging researcher, geneticist, and biostatistician.He is a professor at the University of California, Los Angeles known for developing the Horvath aging clock, which is a highly accurate molecular biomarker of aging, and for developing weighted correlation network analysis.
The first multi-tissue epigenetic clock, Horvath's epigenetic clock, was developed by Steve Horvath, a professor of human genetics and biostatistics at UCLA (Horvath 2013). [10] [11] Horvath spent over 4 years collecting publicly available Illumina DNA methylation data and identifying suitable statistical methods. [12]
But only in 2013, when UCLA aging researcher and bioinformatician Steve Horvath, PhD, created the first epigenetic aging “clock” based on DNA methylation, did it become what scientists ...
Epigenetic Clock Number of CpGs Tissue Publication Epigenetic Predictor of Age 3 Saliva (white blood cells and epithelial cells) Bocklandt et al., 2011 [9] Multi-tissue epigenetic clock 353 51 tissues and cell types Horvath, 2013 [4] Hannum epigenetic clock 71 Whole blood Hannum et al., 2013 [37] PhenoAge 513 Whole blood Levine et al., 2018 [28 ...
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Study co-author says he ‘could hardly believe the profound epigenetic rejuvenation effects’ New compound from pig blood reverses ageing in rats, groundbreaking study claims Skip to main content
Advances in big data analysis allowed for the new types of "aging clocks" to be developed. The epigenetic clock is a promising biomarker of aging and can accurately predict human chronological age. [6] Basic blood biochemistry and cell counts can also be used to accurately predict the chronological age. [7]
2013 The pan-tissue Epigenetic clock is a molecular biomarker by Steve Horvath that facilitates the measurement of the age of all human tissues based on cytosine methylation. [85] 2013 The scientific journal Cell published the article "The Hallmarks of Aging", that was translated to several languages and determined the directions of many ...