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However, material silica gel removes moisture by adsorption onto the surface of its numerous pores rather than by absorption into the bulk of the gel. Silica gel is able to adsorb up to 37% of its own weight in moisture in high-humidity environments. [7] This moisture can be released upon heating at about 120 °C (248 °F) [8] [7] for 1–2 ...
An excipient is a substance formulated alongside the active ingredient of a medication.They may be used to enhance the active ingredient’s therapeutic properties; to facilitate drug absorption; to reduce viscosity; to enhance solubility; to improve long-term stabilization (preventing denaturation and aggregation during the expected shelf life); or to add bulk to solid formulations that have ...
The increased water content in gels increases the chances of microbial or fungal attack, [5] [8] which may contaminate the gel, making it unsuitable for use. Considering the direct route of administration, drugs must be very small in size to have an effective plasma concentration for action.
Adsorption of water in sodium aluminosilicate which is FDA approved (see below) used as molecular sieve in medical containers to keep contents dry and as food additive having E-number E-554 (anti-caking agent); Preferred for static dehydration in closed liquid or gas systems, e.g., in packaging of drugs, electric components and perishable ...
Desiccant dehumidifiers (known also as absorption dehumidifiers) bond moisture with hydrophilic materials such as silica gel. Cheap domestic units contain single-use hydrophilic substance cartridges, gel, or powder. Larger commercial units regenerate the sorbent by using hot air to remove moisture and expel humid air outside the room.
Canisters are commonly filled with silica gel and other molecular sieves as desiccants in drug containers to keep contents dry Silica gel in a sachet or porous packet. A desiccant is a hygroscopic substance that is used to induce or sustain a state of dryness (desiccation) in its vicinity; it is the opposite of a humectant.
Moisture sorption isotherm. The relationship between water content and equilibrium relative humidity of a material can be displayed graphically by a curve, the so-called moisture sorption isotherm. For each humidity value, a sorption isotherm indicates the corresponding water content value at a given temperature. If the composition or quality ...
The blue silica gel in the space below the platform is used as the desiccant. Desiccators are sealable enclosures containing desiccants used for preserving moisture-sensitive items such as cobalt chloride paper for another use. A common use for desiccators is to protect chemicals which are hygroscopic or which react with water from humidity.
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