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In men, 2-3 cases per 10,000 are treated as outpatients and 1-2 cases/10,000 require admission. [36] Young women are most often affected. Infants and the elderly are also at increased risk, reflecting anatomical changes and hormonal status. [36] Xanthogranulomatous pyelonephritis is most common in middle-aged women. [25]
Rates of asymptomatic bacteria in the urine among men over 75 are between 7–10%. [11] 2–10% of pregnant women have asymptomatic bacteria in the urine and higher rates are reported in women who live in some underdeveloped countries. [108] Urinary tract infections may affect 10% of people during childhood. [7]
About 150 million people develop a urinary tract infection in a given year. [5] They are more common in women than men. [3] Up to 10% of women have a urinary tract infection in a given year, and half of women have at least one infection at some point in their lifetime.
In the EU, cefepime/enmetazobactam is indicated for the treatment of complicated urinary tract infections, including pyelonephritis; [2] hospital-acquired pneumonia, including ventilator-associated pneumonia; [2] and the treatment of people with bacteremia that occurs in association with, or is suspected to be associated with, any of the ...
Trial 2 (NCT03354598) was a noninferiority trial in which 1660 adult women with uncomplicated urinary tract infections were randomized and treated. [2] Sulopenem/probenecid demonstrated efficacy in participants with ciprofloxacin-resistant pathogens with a composite response rate of 48% compared to a composite response rate of 33% in the ...
Out of the 1,374,392 female deaths reported in the US in 2017, kidney disease was listed as the cause of death for 24,889 women and was reported as the 9th overall cause of death for women in 2017. [45] Out of the 1,439,111 male deaths reported in the US in 2017, kidney disease was not listed in the top 10 causes of death. [45]
Uses of nitrofurantoin include the treatment of uncomplicated urinary tract infections (UTIs) and prophylaxis against UTIs in people prone to recurrent UTIs. [9] It is a first-line therapy for acute uncomplicated cystitis. [21] It is not recommended for empiric treatment of hospital-acquired UTIs. [21]
When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidney infection (pyelonephritis). [9] Symptoms from a lower urinary tract infection include pain with urination, frequent urination, and feeling the need to urinate despite having an empty bladder. [8]