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  2. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  3. Mirtazapine - Wikipedia

    en.wikipedia.org/wiki/Mirtazapine

    Mirtazapine is a very strong H 1 receptor antagonist and, as a result, it can cause powerful sedative and hypnotic effects. [11] A single 15 mg dose of mirtazapine to healthy volunteers has been found to result in over 80% occupancy of the H 1 receptor and to induce intense sleepiness. [92]

  4. Apoquel for Cats: Uses, Dosage, & Side Effects - AOL

    www.aol.com/lifestyle/apoquel-cats-uses-dosage...

    However, since its introduction to the market in 2013, the drug’s efficacy in cats has been subject to extensive study. The post Apoquel for Cats: Uses, Dosage, & Side Effects appeared first on ...

  5. Tetracyclic antidepressant - Wikipedia

    en.wikipedia.org/wiki/Tetracyclic_antidepressant

    Besides mirtazapine, they also block the α 1-adrenergic receptor [citation needed]. Conversely, whereas TCAs have relatively low affinity for the α 2 -adrenergic receptor , mianserin and mirtazapine potently antagonize this receptor, and this action is thought to be involved in their antidepressant effects [ citation needed ] .

  6. Noradrenergic and specific serotonergic antidepressant

    en.wikipedia.org/wiki/Noradrenergic_and_specific...

    Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]

  7. Mianserin - Wikipedia

    en.wikipedia.org/wiki/Mianserin

    Mianserin is the English and German generic name of the drug and its INN Tooltip International Nonproprietary Name and BAN Tooltip British Approved Name, while mianserin hydrochloride is its USAN Tooltip United States Adopted Name, BANM Tooltip British Approved Name, and JAN Tooltip Japanese Accepted Name.

  8. Human equivalent - Wikipedia

    en.wikipedia.org/wiki/Human_equivalent

    Animal models are used to learn more about a disease, its diagnosis and its treatment, with animal models predicting human toxicity in up to 71% of cases. [1] The human equivalent dose (HED) or human equivalent concentration (HEC) is the quantity of a chemical that, when administered to humans, produces an effect equal to that produced in test animals by a smaller dose. [2]

  9. Penicillin for Cats: Uses, Dosage, & Side Effects - AOL

    www.aol.com/lifestyle/penicillin-cats-uses...

    The post Penicillin for Cats: Uses, Dosage, & Side Effects appeared first on CatTime. It falls under the beta-lactam class of antibiotics and is primarily used to treat bacterial infections.