Search results
Results from the WOW.Com Content Network
Di-tert-butyl dicarbonate is a reagent widely used in organic synthesis. [1] Since this compound can be regarded formally as the acid anhydride derived from a tert-butoxycarbonyl (Boc) group, it is commonly referred to as Boc anhydride. This pyrocarbonate reacts with amines to give N-tert-butoxycarbonyl or so-called Boc
tert-Butyloxycarbonyl protecting group. The tert-butyloxycarbonyl protecting group or tert-butoxycarbonyl protecting group [1] (BOC group) is an acid-labile protecting group used in organic synthesis. The BOC group can be added to amines under aqueous conditions using di-tert-butyl dicarbonate in the presence of a base such as sodium hydroxide:
Each HHB of the tert-butyl network were calculated (in absence of steric repulsion) to contribute 0.7 kcal/mol of stabilization. Calculations with one of the tert-butyl substituents with a methyl, ethyl, or isopropyl group result in net repulsion due to the loss of HHBs. [26] In total, this forms the basis of the corset effect. [5]
The unit cell volume is 272.4 Å 3 and density 7.59. [4] SrC 2 O 5 (strontium dicarbonate) is very similar to the lead compound, and also has monoclinic structure with space group P2 1 /c and four formula units per unit cell. At 30 GPa the unit cell has a=4.736 b=8.175 c=7.140 Å and β=91.34°. The unit cell volume is 276.3 Å 3 and density 4. ...
The tert-butoxide is a strong, non-nucleophilic base in organic chemistry. It readily abstracts acidic protons from substrates, but its steric bulk inhibits the group from participating in nucleophilic substitution, such as in a Williamson ether synthesis or an S N 2 reaction. tert-Butyl alcohol reacts with hydrogen chloride to form tert-butyl ...
DEPC-treated (and therefore RNase-free) water is used in handling of RNA in the laboratory to reduce the risk of RNA being degraded by RNases. Water is usually treated with 0.1% v/v DEPC for at least 2 hours at 37 °C and then autoclaved (at least 15 min) to inactivate traces of DEPC. Inactivation of DEPC in this manner yields CO 2 and ethanol ...
tert-Butyl acetate, t-butyl acetate or TBAc is a colorless flammable liquid with a camphor- or blueberry-like smell. It is used as a solvent in the production of lacquers, enamels, inks, adhesives, thinners and industrial cleaners.
Di-tert-butyl dicarbonate diethylpyrocarbonate Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).