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LINE1 (an abbreviation of Long interspersed nuclear element-1, also known as L1 and LINE-1) is a family of related class I transposable elements in the DNA of many groups of eukaryotes, including animals and plants, classified with the long interspersed nuclear elements (LINEs). [1]
The human genome contains an estimated 100,000 truncated and 4,000 full-length LINE-1 elements. [10] Due to the accumulation of random mutations, the sequence of many LINEs has degenerated to the extent that they are no longer transcribed or translated. Comparisons of LINE DNA sequences can be used to date transposon insertions in the genome.
A closed line segment includes both endpoints, while an open line segment excludes both endpoints; a half-open line segment includes exactly one of the endpoints. In geometry , a line segment is often denoted using an overline ( vinculum ) above the symbols for the two endpoints, such as in AB .
For example, the 5' of the Alu SINE is derived from 7SL RNA, a sequence transcribed by RNA Polymerase III, giving rise to the RNA element of SRP, an abundant ribonucleoprotein. [6] The body of SINEs possess an unknown origin but often share much homology with a corresponding LINE which thus allows SINEs to parasitically co-opt endonucleases ...
Common lines and line segments on a circle, including a secant. A straight line can intersect a circle at zero, one, or two points. A line with intersections at two points is called a secant line, at one point a tangent line and at no points an exterior line. A chord is the line segment that joins two distinct points of a circle. A chord is ...
The coordinate-independent definition of the square of the line element ds in an n-dimensional Riemannian or Pseudo Riemannian manifold (in physics usually a Lorentzian manifold) is the "square of the length" of an infinitesimal displacement [2] (in pseudo Riemannian manifolds possibly negative) whose square root should be used for computing curve length: = = (,) where g is the metric tensor ...
Each curve in this example is a locus defined as the conchoid of the point P and the line l.In this example, P is 8 cm from l. In geometry, a locus (plural: loci) (Latin word for "place", "location") is a set of all points (commonly, a line, a line segment, a curve or a surface), whose location satisfies or is determined by one or more specified conditions.
In higher vertebrates such as humans, the segmental plates are laid down during the process of gastrulation and the segmental plates appear on both sides of the mid-line neural epithelium. Later, the process of neurulation occurs in the mid-line and the segmental plates proceed to the side of the neural tube and notochord.