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As discussed previously, vitamin C generally exhibits low toxicity. The LD 50 (the dose that will kill 50% of a population) is generally accepted to be 11,900 milligrams (11.9 grams) per kilogram in rat populations. [23] The American Association of Poison Control Centers has reported zero deaths from vitamin C toxicity in 2018. [24]
The US Recommended Dietary Allowance for vitamin C for adult women is 76 mg/day and for adult men 90 mg/day. Although Linus Pauling was known for highly respectable research in chemistry and biochemistry, he was also known for promoting the consumption of vitamin C in large doses. [25]
Vitamin C megadosage is a term describing the consumption or injection of vitamin C in doses comparable to or higher than the amounts produced by the livers of mammals which are able to synthesize vitamin C. An argument for this, although not the actual term, was described in 1970 in an article by Linus Pauling. Briefly, his position was that ...
Rather than becoming unsafe, they lose potency slowly over time.” If they’re stored in optimal conditions, you can get the most bang for your buck. Best case scenario, the average shelf-life ...
Hypervitaminosis is a condition of abnormally high storage levels of vitamins, which can lead to various symptoms as over excitement, irritability, or even toxicity. Specific medical names of the different conditions are derived from the given vitamin involved: an excess of vitamin A, for example, is called hypervitaminosis A.
A U.K. coroner is pushing the country’s Food Standards Agency to upgrade its labeling of certain dietary supplements, after a man died in part from vitamin D toxicity, or hypervitaminosis D.
[33] [32] According to the U.S. Food and Drug Administration (FDA), high-dose vitamin C (such as intravenous ascorbic acid therapy) has not been approved as a treatment for cancer or any other medical condition. [2] There many been multiple studies devoted to investigating the medicinal properties of ascorbic acid.
Kidney toxicity [5] associated with kidney failure; associated with development of cancer, particularly of the urinary tract, known carcinogen [8] [9] Atractylate Atractylis gummifera: Liver damage, [3] nausea, vomiting, epigastric and abdominal pain, diarrhoea, anxiety, headache and convulsions, often followed by coma [10]