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Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. [ 1 ] [ 2 ] It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of neonatal encephalopathy which may lead to this condition.
Panton–Valentine leukocidin (PVL) is a cytotoxin—one of the β-pore-forming toxins. The presence of PVL is associated with increased virulence of certain strains (isolates) of Staphylococcus aureus .
The initialism PVL may refer to: The paleontological collection of the Fundación-Instituto Miguel Lillo, Universidad Nacional de Tucumán; Parameter Value Language, the data markup language, used by NASA; Panton–Valentine leukocidin, a factor in bacterial virulence; The Pascack Valley Line, a commuter rail line operated by NJ Transit
In population genetics, the genotype frequency is the frequency or proportion (i.e., 0 < f < 1) of genotypes in a population. Although allele and genotype frequencies are related, it is important to clearly distinguish them.
Statistical genetics is a scientific field concerned with the development and application of statistical methods for drawing inferences from genetic data. The term is most commonly used in the context of human genetics. Research in statistical genetics generally involves developing theory or methodology to support research in one of three ...
It is widely used in genetic epidemiology and behavioural genetics. [ 2 ] [ 3 ] The basic ACE model relies on several assumptions, including the absence of assortative mating , [ 4 ] that there is no genetic dominance or epistasis , [ 5 ] that all genetic effects are additive, and the absence of gene-environment interactions . [ 3 ]
The two graphics illustrate sampling distributions of polygenic scores and the predictive ability of stratified sampling on polygenic risk score with increasing age. + The left panel shows how risk—(the standardized PRS on the x-axis)—can separate 'cases' (i.e., individuals with a certain disease, (red)) from the 'controls' (individuals without the disease, (blue)).
Population viability analysis (PVA) is a species-specific method of risk assessment frequently used in conservation biology.It is traditionally defined as the process that determines the probability that a population will go extinct within a given number of years.