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  2. Dronabinol - Wikipedia

    en.wikipedia.org/wiki/Dronabinol

    While dronabinol was initially approved by the United States Food and Drug Administration (FDA) on May 31, 1985, [21] it was not until May 13, 1986, the Drug Enforcement Administration (DEA), issued a Final Rule and Statement of Policy authorizing the "rescheduling of synthetic dronabinol in sesame oil and encapsulated in soft gelatin capsules from Schedule I to Schedule II" (DEA 51 FR 17476-78).

  3. Medical cannabis - Wikipedia

    en.wikipedia.org/wiki/Medical_cannabis

    Relative to inhaled consumption, peak concentration of oral THC is delayed, and it may be difficult to determine optimal dosage because of variability in patient absorption. [ 6 ] In 1964, Albert Lockhart and Manley West began studying the health effects of traditional cannabis use in Jamaican communities.

  4. Medical cannabis in the United States - Wikipedia

    en.wikipedia.org/wiki/Medical_cannabis_in_the...

    Additionally, the cannabis provided by NIDA has been criticized as being inferior to that which is commonly used by medical cannabis patients in states where it is legal. [ 94 ] [ 95 ] [ 96 ] Criticisms of NIDA-supplied cannabis include high amounts of stems and seeds, [ 97 ] high mold and yeast levels, [ 98 ] low THC content, [ 24 ] and low ...

  5. Effects of cannabis - Wikipedia

    en.wikipedia.org/wiki/Effects_of_cannabis

    In dogs, the minimum lethal dose of THC is over 3000 mg/kg. [20] According to The Merck Index, [21] the LD 50 of THC (the dose which causes the death of 50% of individuals) is 1270 mg/kg for male rats and 730 mg/kg for female rats from oral consumption in sesame oil, and 42 mg/kg for rats from inhalation. [22]

  6. Nabiximols - Wikipedia

    en.wikipedia.org/wiki/Nabiximols

    Nabiximols [2] sold under the brand name Sativex, is a specific Cannabis extract that was approved in 2010 as a botanical drug in the United Kingdom. Nabiximols is sold as a mouth spray intended to alleviate neuropathic pain , spasticity , overactive bladder , and other symptoms of multiple sclerosis ; it was developed by the UK company GW ...

  7. Is it safe to drive after taking a cannabis edible? Here's ...

    www.aol.com/lifestyle/safe-drive-taking-cannabis...

    A 2022 study published in the Journal of Psychopharmacology found that participants given oral cannabis (the lab-grade alternative to an edible) showed low blood THC concentration at the height of ...

  8. Tetrahydrocannabinol - Wikipedia

    en.wikipedia.org/wiki/Tetrahydrocannabinol

    There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [22] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...

  9. Jury awards $20 million to family of a man with sleep apnea ...

    www.aol.com/entertainment/jury-awards-20-million...

    A Palm Beach County jury has awarded $20 million to the family of a Boca Raton man who was being treated with painkillers by a doctor who failed to ask whether the patient suffered from sleep apnea.

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