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Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.
Programmed cell death (PCD; sometimes referred to as cellular suicide [1]) is the death of a cell as a result of events inside of a cell, such as apoptosis or autophagy. [2] [3] PCD is carried out in a biological process, which usually confers advantage during an organism's lifecycle.
John Foxton Ross Kerr AO (24 January 1934 – 4 June 2024) was an Australian pathologist.He was the first to describe the ultrastructural changes in apoptosis, and could show that they differ significantly from the changes that occur in necrosis, another form of cell death.
Adler Berriman "Barry" Seal (July 16, 1939 – February 19, 1986) was an American commercial airline pilot who became a major drug smuggler for the Medellín Cartel.When Seal was convicted of smuggling charges, he became an informant for the Drug Enforcement Administration and testified in several major drug trials.
Cell growth plays a crucial role in cell proliferation, regulating cellular homeostasis and cell cycle progression through dynamic changes in cell size. [1] And like DNA damage, it can promote senescence by triggering a prolonged cell cycle arrest. [5]
Cancer cells are cells that divide continually, forming solid tumors or flooding the blood or lymph with abnormal cells.Cell division is a normal process used by the body for growth and repair.
In law, medicine, and statistics, cause of death is an official determination of the conditions resulting in a human's death, which may be recorded on a death certificate.
Cellular immunity protects the body through: T-cell mediated immunity or T-cell immunity: activating antigen-specific cytotoxic T cells that are able to induce apoptosis in body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;