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Cyproheptadine, sold under the brand name Periactin among others, is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties. It was patented in 1959 and came into medical use in 1961. [ 5 ]
Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .
flunixin meglumine – nonsteroidal anti-inflammatory drug used as an analgesic and antipyretic in horses; fluralaner - antiparasitic; frunevetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in cats; furosemide – diuretic used to prevent exercise-induced pulmonary hemorrhage in horses
However, horses with a low body condition score lack the fat reserves for strenuous work and also may lack lean muscle. [10] Horses with a very high body condition score carry too much weight, which interferes with stamina and biomechanics. Some studies addressed the relationship of body condition score and endurance performance in endurance races.
Namib horse in poor body condition in February. The horse body mass is always 65-75 % water. [1] The horse is considered a "thin animal" (with little fat), whose weight is divided into approximately 11% bone, 50% muscle and 9% fat; [2] but a large number of factors influence its weight.
Dose a Time to peak Half-life b Metabolism Anticholinergic Diphenhydramine: 50 mg 2–3 hours 2–9 hours CYP2D6, others Yes Doxylamine: 25 mg 2–3 hours 10–12 hours CYP2D6, others Yes Hydroxyzine: 25–100 mg 2 hours 20 hours ADH, CYP3A4, others No Doxepin: 3–6 mg 2–3 hours 17 hours c: CYP2D6, others No (at low doses) Mirtazapine: 7.5 ...
Related: A Guide to Cooking With Any Type of Coconut, From Coconut Oil to Coconut Cream.
A Dosage Index of under 4.00 is considered optimal for horses attempting to win classic races. [7] As the Dosage Profile and Index are widely published, breeders may select mates for their mare with these figures in mind, especially if they are intending to sell the foal at auction.