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In 2013, it provided necessary data, which addressed 10 specific biological agent knowledge gaps, to improve hazard, risk, and threat assessments. The data allowed for significant growth in the credibility of hazard and risk assessment modeling of bioterrorism scenarios for a variety of toxin threat agents, including both bacteria and viruses.
Under United States law, Biological select agents or toxins (BSATs)—or simply select agents for short—are bio-agents which (since 1997 [1]) have been declared by the U.S. Department of Health and Human Services (HHS) or by the U.S. Department of Agriculture (USDA) to have the "potential to pose a severe threat to public health and safety".
They inspect the laboratories of more than 300 organizations approved to use and transfer select agents, and put regulations in place to minimize risk in the use of these bacterial agents and toxins. [1] DSAT investigates incidents related to the laboratory use of select agents and toxins and refers cases to the FBI and HHS Office of Inspector ...
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Not all select agents require BSL-4 handling, namely select bacteria and toxins, but most select agent viruses do (with the notable exception of SARS-CoV-1 which can be handled in BSL3). Many non-select agent viruses are often handled in BSL-4 according to facility SOPs or when dealing with new viruses closely related to viruses that require BSL-4.
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Since 1997, United States law has declared a list of bio-agents designated by the U.S. Department of Health and Human Services or the U.S. Department of Agriculture that have the "potential to pose a severe threat to public health and safety" to be officially defined as "select agents" and possession or transportation of them are tightly controlled as such. [5]
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