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IARC group 2A agents are substances and exposure circumstances that have been classified as probable carcinogens by the International Agency for Research on Cancer (IARC). [1] This designation is applied when there is limited evidence of carcinogenicity in humans, as well as sufficient evidence of carcinogenicity in experimental animals .
Dichloromethane (DCM, methylene chloride, or methylene bichloride) is an organochlorine compound with the formula C H 2 Cl 2. This colorless, volatile liquid with a chloroform -like, sweet odor is widely used as a solvent .
Exposure to cancer-causing chemicals (carcinogens) may cause mutations that allow cells to grow out of control, causing cancer. Carcinogens in the workplace may include chemicals like anilines , chromates , dinitrotoluenes , arsenic and inorganic arsenic compounds, beryllium and beryllium compounds, cadmium compounds, and nickel compounds. [ 1 ]
IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as [1] This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.
May cause cancer and heritable genetic damage R48/20 Harmful: danger of serious damage to health by prolonged exposure through inhalation R48/21 Harmful: danger of serious damage to health by prolonged exposure in contact with skin R48/22 Harmful: danger of serious damage to health by prolonged exposure if swallowed R48/20/21
The manifestations of exposure to health hazards during the production process often occurs at a low level and the effects of the toxins may take decades to surface. Use of toxic materials such as arsine, phosphine and others potentially expose workers to health hazards which include cancer, miscarriages and birth defects.
Exposure to certain chemicals can cause acute or long-term adverse health effects. Chemical hazards are usually classified separately from biological hazards (biohazards). Chemical hazards are classified into groups that include asphyxiants, corrosives, irritants, sensitizers, carcinogens, mutagens, teratogens, reactants, and flammables. [1]
The handling of this chemical may incur notable safety precautions. ... log 10 of Dichloromethane vapor pressure. Uses formula: ...