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Loop diuretics are pharmacological agents that primarily inhibit the Na-K-Cl cotransporter located on the luminal membrane of cells along the thick ascending limb of the loop of Henle. [4] They are often used for the treatment of hypertension and edema secondary to congestive heart failure , liver cirrhosis , or chronic kidney disease .
Low-dose thiazides are tolerated as well as the other classes of medications for hypertension, including ACE inhibitors, beta blockers and calcium channel blockers. [9] In general, the thiazides and thiazide-like diuretics reduce the risk of death, stroke, heart attack , and heart failure due to hypertension.
Both thiazide diuretics and thiazide-like diuretics are effective in reducing risk of stroke. [ 5 ] [ 6 ] [ 7 ] Both drug classes appear to have comparable rates of adverse effects as other antihypertensives such as angiotensin II receptor blockers and dihydropyridine calcium channel blockers and lesser prevalence of side-effects when compared ...
Calcium supplements may be a bonus for bone health. But if you’re taking these medications, your supplement might backfire. 5 Ways Your Calcium Supplement May Interact with Medications ...
[1] [2] [3] Subgroup C03 is part of the anatomical group C Cardiovascular system. [4] Codes for veterinary use (ATCvet codes) can be created by placing the letter Q in front of the human ATC code: for example, QC03. [5] ATCvet codes without corresponding human ATC codes are cited with the leading Q in the following list.
Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle. This results in excretion of sodium, chloride and water, and thus acts as a diuretic. [1] Although trichlormethiazide is used to treat hypertension, its hypotensive effects may not necessarily be due to its role as a ...
Thiazide diuretics increase the excretion of sodium and potassium ions and decrease the excretion of calcium ions and uric acid so they are contraindicated in patients with hyponatraemia, hypokalaemia, hypercalcaemia and hyperuricaemia. They are also contraindicated in patients with Addison's disease.
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