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  2. Western blot - Wikipedia

    en.wikipedia.org/wiki/Western_blot

    Western blot workflow. The western blot (sometimes called the protein immunoblot), or western blotting, is a widely used analytical technique in molecular biology and immunogenetics to detect specific proteins in a sample of tissue homogenate or extract. [1]

  3. Western blot normalization - Wikipedia

    en.wikipedia.org/wiki/Western_blot_normalization

    Normalization of Western blot data is an analytical step that is performed to compare the relative abundance of a specific protein across the lanes of a blot or gel under diverse experimental treatments, or across tissues or developmental stages.

  4. Immunostaining - Wikipedia

    en.wikipedia.org/wiki/Immunostaining

    Western blotting allows the detection of specific proteins from extracts made from cells or tissues, before or after any purification steps. Proteins are generally separated by size using gel electrophoresis before being transferred to a synthetic membrane via dry, semi-dry, or wet blotting methods. The membrane can then be probed using ...

  5. Blot (biology) - Wikipedia

    en.wikipedia.org/wiki/Blot_(biology)

    Similar to a western blot, the far-western blot uses protein–protein interactions to detect the presence of a specific protein immobilized on a blotting matrix. Antibodies are then used to detect the presence of the protein–protein complex, making the Far-Western blot a specific case of the Western blot.

  6. Far-western blot - Wikipedia

    en.wikipedia.org/wiki/Far-Western_blot

    The far-western blot, or far-western blotting, is a molecular biological method based on the technique of western blot to detect protein-protein interaction in vitro. [1] [2] Whereas western blot uses an antibody probe to detect a protein of interest, far-western blot uses a non-antibody probe which can bind the protein of interest.

  7. Immunoprecipitation - Wikipedia

    en.wikipedia.org/wiki/Immunoprecipitation

    After washing, the precipitated protein(s) are eluted and analyzed by gel electrophoresis, mass spectrometry, western blotting, or any number of other methods for identifying constituents in the complex. Protocol times for immunoprecipitation vary greatly due to a variety of factors, with protocol times increasing with the number of washes ...

  8. Polyacrylamide gel electrophoresis - Wikipedia

    en.wikipedia.org/wiki/Polyacrylamide_gel...

    Western blotting is a process by which proteins separated in the acrylamide gel are electrophoretically transferred to a stable, manipulable membrane such as a nitrocellulose, nylon, or PVDF membrane. It is then possible to apply immunochemical techniques to visualise the transferred proteins, as well as accurately identify relative increases ...

  9. Immunoscreening - Wikipedia

    en.wikipedia.org/wiki/Immunoscreening

    Immunoscreening is a method of biotechnology used to detect a polypeptide produced from a cloned gene.The term encompasses several different techniques designed for protein identification, such as Western blotting, using recombinant DNA, and analyzing antibody-peptide interactions.

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