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PhF behaves rather differently from other halobenzene derivatives owing to the pi-donor properties of fluoride. For example, the para position is more activated than benzene toward electrophiles. For this reason, it can be converted to 1-bromo-4-fluorobenzene with relatively high efficiency. [3]
Download as PDF; Printable version; In other projects Wikidata item; Appearance. ... Halobenzene may also refer to any of the monosubstituted halobenzenes: Fluorobenzene;
The +M effect, also known as the positive mesomeric effect, occurs when the substituent is an electron donating group. The group must have one of two things: a lone pair of electrons, or a negative charge. In the +M effect, the pi electrons are transferred from the group towards the conjugate system, increasing the density of the system.
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However, another effect that plays a role is the +M effect which adds electron density back into the benzene ring (thus having the opposite effect of the -I effect but by a different mechanism). This is called the mesomeric effect (hence +M) and the result for fluorine is that the +M effect approximately cancels out the -I effect.
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The United States Food and Drugs Administration is warning pet owners about a common medication given to pets to treat arthritis. The F.D.A. now says that the drug Librela may be associated with ...
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