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When the initial phenylethylamine concentration in the brain is low, brain levels can be increased 1000-fold when taking a monoamine oxidase inhibitor (MAOI), particularly a MAO-B inhibitor, and by 3–4 times when the initial concentration is high. [65]
Common side effects include a fast heart beat, high blood pressure, trouble sleeping, dizziness, and restlessness. [3] Serious side effects may include abuse , but do not include pulmonary hypertension or valvular heart disease , as the latter were caused by the fenfluramine component of the fen-phen drug combination . [ 3 ]
Other effects that were noted included profuse salivation and piloerection. Phenylethanolamine also produced behavioral effects such as stereotyped head movement, rapid eye movement, and repetitive tongue extrusion. These and other observations were suggested to be consistent with an action on α- and β-adrenergic receptors. [15]
Phenylalanine (symbol Phe or F) [3] is an essential α-amino acid with the formula C 9 H 11 NO 2.It can be viewed as a benzyl group substituted for the methyl group of alanine, or a phenyl group in place of a terminal hydrogen of alanine.
N-Methylphenethylamine (NMPEA) is a naturally occurring trace amine neuromodulator in humans that is derived from the trace amine, phenethylamine (PEA). [2] [3] It has been detected in human urine (<1 μg over 24 hours) [4] and is produced by phenylethanolamine N-methyltransferase with phenethylamine as a substrate, which significantly increases PEA's effects.
It’s also packed with nutrients, including antioxidants, flavonoids and the stimulant phenylethylamine, a chemical that boosts feel-good serotonin and endorphins. Serotonin is also known to ...
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; [note 1] the class is composed of all the derivative compounds of phenethylamine which can be formed by replacing, or substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents.
Lighter Side. Medicare. News. Science & Tech. Shopping. Sports. Weather. 24/7 Help. ... but the more significant health effects come from the visceral fat that’s not visible. While some fat is ...