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Pharmaceutical companies often use freeze-drying to increase the shelf life of the products, such as live virus vaccines, [19] biologics, [20] and other injectables. By removing the water from the material and sealing the material in a glass vial , the material can be easily stored, shipped, and later reconstituted to its original form for ...
IMA Life also offers freeze-drying technology: industrial, pilot and laboratory freeze dryers. IMA Life designs, manufactures, installs and services integrated systems predominantly for the pharmaceutical primary packaging market. It has been in the market of freeze dryer manufacturing for more than 50 years.
A Zydis tablet is produced by lyophilizing or freeze-drying the drug in a matrix usually consisting of gelatin. The resulting product is very lightweight and fragile, and must be dispensed in a special blister pack. Amipara et al., in their article "Oral disintirating tablet of antihypertensive drug" explain the technology's limitations:
Freeze drying or lyophilization is a drying method where the solvent is frozen prior to drying and is then sublimed, i.e., passed to the gas phase directly from the solid phase, below the melting point of the solvent. It is increasingly applied to dry foods, beyond its already classical pharmaceutical or medical applications.
Pharmaceutical formulation, in pharmaceutics, ... Lyophilization, or freeze drying, is a process that removes water from a liquid drug creating a solid powder, or ...
This usually requires the addition of substances which protect the cells during freezing and thawing (cryoprotectants), 3) preservation of organs under hypothermic conditions for transplantation, 4) lyophilization (freeze-drying) of pharmaceuticals, 5) cryosurgery, a (minimally) invasive approach for the destruction of unhealthy tissue using ...
It designs and manufactures automatic machines for the processing and packaging of pharmaceuticals, cosmetics, tea and coffee.It specializes in tea bagging and coffee pod machines, solid dose manufacturing, sterile processing equipment, liquid filling, freeze-drying, labelling, blistering, counting, tube filling, end-of-line and cartoning machines.
In 1971, King published a book, Freeze Drying of Foods. [10] King also gave a fundamental understanding of the phenomenon of product collapse during freeze drying and how to avoid it. That research was also valuable to the pharmaceutical industry which also often uses freeze drying.
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