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This is most likely due to a mechanism allowing the cell to sense changes within the environment, thus influencing change in gene expression. [62] Understanding how these strain changes occur from being low or non-pathogenic to being highly pathogenic and vice versa may aid in developing novel therapeutics for microbial infections.
The Journal of Bacteriology is a monthly peer-reviewed scientific journal established in 1916. It is published by the American Society for Microbiology and the editor in chief is George A. O'Toole Jr. ( Dartmouth College ).
A GBD study estimated the global death rates from (33) bacterial pathogens, finding such infections contributed to one in 8 deaths (or ~7.7 million deaths), which could make it the second largest cause of death globally in 2019. [6] [3] Most pathogenic bacteria can be grown in cultures and identified by Gram stain and other methods.
The new virus capsule that contains part bacterial DNA then infects another bacterial cell. When the bacterial DNA packaged into the virus is inserted into the recipient cell three things can happen to it: [citation needed] [5] The DNA is recycled for spare parts. If the DNA was originally a plasmid, it will re-circularize inside the new cell ...
Corynebacterium diphtheriae is the bacterium that causes the disease called diphtheria. Bacteriophages introduce a gene into the bacterial cells that makes a strain toxigenic. The strains that are not infected with these viruses are harmless. [5] C. diphtheriae is a rod-shaped, Gram-positive, non spore-forming, and nonmotile bacterium. [17]
Bacteriology is the study of bacteria and their relation to medicine. Bacteriology evolved from physicians needing to apply the germ theory to address the concerns relating to disease spreading in hospitals the 19th century. [5] Identification and characterizing of bacteria being associated to diseases led to advances in pathogenic bacteriology.
However, bacteriocins can also induce death by translocating into the periplasmic space and cleaving DNA non-specifically (colicin E2), inactivating the ribosome (colicin E3), inhibiting synthesis of peptidoglycan, a major component of the bacterial cell wall (colicin M). [19] Bacteriocins have immense potential to treat human disease.
The bacterial disease tuberculosis, primarily caused by Mycobacterium tuberculosis, has one of the highest disease burdens, killing 1.6 million people in 2021, mostly in Africa and Southeast Asia. [16] Bacterial pneumonia is primarily caused by Streptococcus pneumoniae, Staphylococcus aureus, Klebsiella pneumoniae, and Haemophilus influenzae. [17]