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Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
A reference range is usually defined as the set of values 95 percent of the normal ... a reference range for a blood test ... Beta human chorionic gonadotrophin (β-hCG)
There is a multilevel urine pregnancy test (MLPT) that measures hCG levels semiquantitatively. The hCG levels are measured at <25, 25 to 99, 100 to 499, 500 to 1999, 2000 to 9999, and >10,000 mIU/mL. This test has utility for determining the success of medication abortion. [13] [14] Single intrauterine pregnancy, first trimester.
1082 n/a Ensembl ENSG00000104827 n/a UniProt P0DN86 n/a RefSeq (mRNA) NM_000737 n/a RefSeq (protein) NP_000728.1 NP_149032.1 NP_149133.1 NP_149439.1 NP_149032 NP_149439 n/a Location (UCSC) Chr 19: 49.02 – 49.02 Mb n/a PubMed search n/a Wikidata View/Edit Human Choriogonadotropin subunit beta (CG-beta) also known as chorionic gonadotrophin chain beta is a protein that in humans is encoded by ...
The term "multiple-marker screening test" is sometimes used instead. [1] [2] This term can encompass the "double test" and "quadruple test" (described below). The Triple screen measures serum levels of AFP, estriol, and beta-hCG, with a 70% sensitivity and 5% false-positive rate.
The presence of hCG in a woman's body indicates that a fertilized egg has implanted in the uterus and the placenta has started to form. 10 days after fertilization, significant hCG can be detected from woman's blood sample. [6] The levels of hCG in the body increase rapidly in the first few weeks of pregnancy, doubling every 48–72 hours. [7]
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The standard definition of a reference range for a particular measurement is defined as the interval between which 95% of values of a reference population fall into, in such a way that 2.5% of the time a value will be less than the lower limit of this interval, and 2.5% of the time it will be larger than the upper limit of this interval, whatever the distribution of these values.
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