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  2. Phase-contrast microscopy - Wikipedia

    en.wikipedia.org/wiki/Phase-contrast_microscopy

    Phase-contrast microscopy is particularly important in biology. It reveals many cellular structures that are invisible with a bright-field microscope, as exemplified in the figure. These structures were made visible to earlier microscopists by staining, but this required additional preparation and death of the cells. The phase-contrast ...

  3. Live-cell imaging - Wikipedia

    en.wikipedia.org/wiki/Live-cell_imaging

    As living cells are translucent, they must be stained to be visible in a traditional light microscope. Unfortunately, the process of staining cells generally kills them. With the invention of the phase-contrast microscopy it became possible to observe unstained living cells in detail. After its introduction in the 1940s, live-cell imaging ...

  4. Phase-contrast imaging - Wikipedia

    en.wikipedia.org/wiki/Phase-contrast_imaging

    Phase-contrast imaging is the highest resolution imaging technique ever developed, and can allow for resolutions of less than one angstrom (less than 0.1 nanometres). It thus enables the direct viewing of columns of atoms in a crystalline material. [20] [21] The interpretation of phase-contrast images is not a straightforward task.

  5. Dark-field microscopy - Wikipedia

    en.wikipedia.org/wiki/Dark-field_microscopy

    Dark-field microscopy produces an image with a dark background Operating principles of dark-field and phase-contrast microscopies Dark-field microscopy is a very simple yet effective technique and well suited for uses involving live and unstained biological samples, such as a smear from a tissue culture or individual, water-borne, single-celled ...

  6. Quantitative phase-contrast microscopy - Wikipedia

    en.wikipedia.org/wiki/Quantitative_phase...

    Quantitative phase contrast microscopy or quantitative phase imaging are the collective names for a group of microscopy methods that quantify the phase shift that occurs when light waves pass through a more optically dense object. [1] [2] Translucent objects, like a living human cell, absorb and scatter small amounts of light.

  7. Patching and Capping - Wikipedia

    en.wikipedia.org/wiki/Patching_and_Capping

    In other words, phase contrast is a contrast-enhancing optical technique that can be used to produce high contrast images such as living cells and subcellular including nuclei and other organelles. One of the major advantages of using phase contrast microscopy is that living cells can be examined in their natural state without being killed ...

  8. Moral Injury: The Grunts - The Huffington Post

    projects.huffingtonpost.com/moral-injury/the...

    In contrast to Post-Traumatic Stress Disorder, which springs from fear, moral injury is a violation of what each of us considers right or wrong. The diagnosis of PTSD has been defined and officially endorsed since 1980 by the mental health community, and those suffering from it have earned broad public sympathy and understanding.

  9. Bright-field microscopy - Wikipedia

    en.wikipedia.org/wiki/Bright-field_microscopy

    Bright-field microscopy (BF) is the simplest of all the optical microscopy illumination techniques. Sample illumination is transmitted (i.e., illuminated from below and observed from above) white light , and contrast in the sample is caused by attenuation of the transmitted light in dense areas of the sample.