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Drugs affected by grapefruit juice; Drug class Major Interactions Minor interactions Antiarrhythmic agents: amiodarone (Cordarone) dronedarone dofetilide (Tikosyn) Antihistamines: terfenadine (Seldane) (off the market) diphenhydramine (partially) astemizole (off the market) Calcium channel antagonists: felodipine (Plendil)
"There are certain substances in grapefruit juice and grapefruit that may affect the way the body handles a medication," says Leonard. "This can result in fluctuating levels of a medication in the ...
Lercanidipine (trade name Zanidip, among others) is an antihypertensive (blood pressure lowering) drug. It belongs to the dihydropyridine class of calcium channel blockers, which work by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. This lowers the blood pressure and allows the heart to work ...
Calcium channel blockers (CCBs) preferentially block the L-type voltage-gated calcium channels to prevent the flow of calcium influx in the blood vessels and the heart, thereby reducing peripheral vascular resistance and cardiac output respectively. [10] Dihydropyridines (DHP): amlodipine, nifedipine, felodipine, nicardipine
Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists [2] are a group of medications that disrupt the movement of calcium (Ca 2+) through calcium channels. [3] Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension.
7 Calcium channel blockers. 8 Antimineralocorticoid. 9 Antiplatelet drug. 10 Anticoagulant. 11 Fibrinolytics. 12 Diuretics. 13 References. Toggle the table of contents.
Drugs that decrease breaking down of carbamazepine or otherwise increase its levels include erythromycin, [32] cimetidine, propoxyphene, and calcium channel blockers. [18] Grapefruit juice raises the bioavailability of carbamazepine by inhibiting the enzyme CYP3A4 in the gut wall and in the liver. [5]
Nifedipine, sold under the brand name Procardia among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. [2] It is one of the treatments of choice for Prinzmetal angina. [2] It may be used to treat severe high blood pressure in pregnancy. [2]