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Phenylbutazone, often referred to as "bute", [1] is a nonsteroidal anti-inflammatory drug (NSAID) for the short-term treatment of pain and fever in animals.. In the United States and United Kingdom, it is no longer approved for human use (except in the United Kingdom for ankylosing spondylitis), as it can cause severe adverse effects such as suppression of white blood cell production and ...
It is a prodrug of the non-steroidal anti-inflammatory drug (NSAID) phenylbutazone, [1] and is commonly used in horses. [2] ... Phenylbutazone [50-33-9] (1) is ...
Due to the major adverse effects of phenylbutazone, the replacement by tepoxalin was made to reduce muscular pain in 2003. [9] In horses, the drug is intravenously administered at 10 mg/kg on a daily dose for 10 days. [9] Doses may be doubled or tripled to treat severe pain, such as laminitis.
In horses, this includes gastric ulcers, [8] right dorsal colitis, [9] and nephrotoxicity. [10] Flunixin is a prohibited substance under International Federation for Equestrian Sports rules, [11] and its use is prohibited or restricted by many other equestrian organizations. At labeled dose (1.1 mg/kg) given IV, detection time was found to be ...
pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for seizures; phenylbutazone – nonsteroidal anti-inflammatory drug (NSAID) phenylpropanolamine – controls urinary incontinence in dogs
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