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Bromocriptine, originally marketed as Parlodel and subsequently under many brand names, [1] is an ergoline derivative and dopamine agonist that is used in the treatment of pituitary tumors, Parkinson's disease, hyperprolactinaemia, neuroleptic malignant syndrome, and, as an adjunct, type 2 diabetes.
Bromocriptine is a D 2 receptor agonist and D 1 receptor antagonist with a binding affinity to D 2 receptors of anterior pituitary cells, exclusively on lactotrophs. Bromocriptine stimulates Na + , K + -ATPase activity and/or cytosolic Ca 2+ elevation and therefore reduction of prolactin which leads to no production of cAMP.
The growth in commercial use of paper towels can be attributed to the migration from folded towels (in public bathrooms, for example) to roll towel dispensers, which reduces the amount of paper towels used by each patron. [12] Within the forest products industry, paper towels are a major part of the "tissue market", second only to toilet paper ...
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[1] [53] [54] A systematic review and meta-analysis has shown that cabergoline and quinagolide are more effective in the treatment of hyperprolactinemia compared to bromocriptine, [55] this is because evidence had suggested fewer side effects, rapid titration and offers better dosing interval in medication like quinagolide compared to ...
Pope Francis has revealed he was the target of an attempted suicide bombing during his visit to Iraq three years ago, the first by a Catholic pontiff to the country and probably the riskiest ...
Cabergoline is frequently used as a first-line agent in the management of prolactinomas due to its higher affinity for D 2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine, though in pregnancy bromocriptine is often still chosen since there is less data on safety in pregnancy for ...
Hozier tweeted his excitement for being the musical guest, writing on X, "Wild way to end this year. Can't wait." On the Instagram post announcing the pairing of Short and Hozier for the final ...