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Microvascular decompression (MVD), also known as the Jannetta procedure, [1] is a neurosurgical procedure used to treat trigeminal neuralgia (along with other cranial nerve neuralgias), a pain syndrome characterized by severe episodes of intense facial pain, and hemifacial spasm.
Trigeminal neuralgia (TN or TGN), also called Fothergill disease, tic douloureux, trifacial neuralgia, or suicide disease, is a long-term pain disorder that affects the trigeminal nerve, [7] [1] the nerve responsible for sensation in the face and motor functions such as biting and chewing.
1933: first published carpal tunnel surgery for post-traumatic compression [58] 1946: first carpal tunnel surgery for idiopathic compression [59] [49] 1958: cubital tunnel surgery described [60] [50] 1962: tarsal tunnel surgery described [52] 1967: Janetta procedure for trigeminal neuralgia [61] 1989: endoscopic carpal tunnel surgery [62]
The trigeminal nerve.. ATN is usually attributed to inflammation or demyelination, with increased sensitivity of the trigeminal nerve.These effects are believed to be caused by infection, demyelinating diseases, or compression of the trigeminal nerve (by an impinging vein or artery, a tumor, dental trauma, accidents, or arteriovenous malformation) and are often confused with dental problems.
Peter Joseph Jannetta (April 5, 1932 – April 11, 2016) was an American neurosurgeon known for devising microvascular decompression, a surgical procedure to treat trigeminal neuralgia. At the University of Pittsburgh School of Medicine , he was the first Walter Dandy Professor of Neurological Surgery.
In the United States, carbamazepine is indicated for the treatment of epilepsy (including partial seizures, generalized tonic-clonic seizures and mixed seizures), and trigeminal neuralgia. [4] [18] Carbamazepine is the only medication that is approved by the Food and Drug Administration for the treatment of trigeminal neuralgia. [19]
First line treatments are certain antidepressants (tricyclic antidepressants and serotonin–norepinephrine reuptake inhibitors), and anticonvulsants (pregabalin and gabapentin). [26] [27] Opioid analgesics are recognized as useful agents but are not recommended as first line treatments. [27] A broader range of treatments are used in specialist ...
The recommended first-line preventive therapy is verapamil, a calcium channel blocker. [ 2 ] [ 49 ] Verapamil was previously underused in people with cluster headache. [ 8 ] Improvement can be seen in an average of 1.7 weeks for episodic cluster headache and 5 weeks for chronic cluster headache when using a dosage of ranged between 160 and 720 ...
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