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Future approaches of NRT could include nicotine preloading, a true pulmonary inhaler, and nicotine vaccines. [8] Nicotine preloading, otherwise known as pre-cessation or pre-quitting NRT, has found that using the patch for a few weeks before the quit date produces significantly higher quit rates than if it was started on the quit day. [8]
Nicotine is a secondary metabolite produced in a variety of plants in the family Solanaceae, most notably in tobacco Nicotiana tabacum, where it can be found at high concentrations of 0.5 to 7.5%. [180] Nicotine is also found in the leaves of other tobacco species, such as Nicotiana rustica (in amounts of 2–14%).
Nicorette is the brand name of a number of products for nicotine replacement therapy (NRT) that contain nicotine polacrilex. Developed in the late 1970s in Sweden by AB Leo [ sv ] in the form of a chewing gum, Nicorette was the first nicotine replacement product on the market.
Nicorette, Nicotinell, Niquitin, Boots NicAssist, Commit, Habitrol, Nicoderm CQ, Nicotrol, Thrive 3-[(2S)-1-methylpyrrolidine-2-yl]pyridine Transdermal patch, gum, inhaler, nasal spray, lozenge, microtab, and is naturally found in tobacco Agonist of the nicotinic receptor, [31] both Ganglion type and α 4 β 2 [32] Treatment of tobacco ...
Kind Consumer Limited was a UK-based company that developed Voke, a nicotine inhaler intended to address tobacco harm reduction. The company was founded in 2006 by Alex Hearn, a British inventor and entrepreneur based in London. [1] [2] [3] The company collapsed into administration in 2020, after raising £140m in funding from investors. [4]
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Nicotine replacement therapy products (e.g. chewing gum, lozenges, transdermal systems) are indicated as temporary aids for cigarette smokers who want to give up smoking. They serve as alternative sources of nicotine and provide relief of nicotine withdrawal symptoms in nicotine-dependent individuals who are acutely withdrawing from cigarette ...
These include nicotine lozenges, nicotine gum and inhalers, nicotine patches, and electronic cigarettes. In a review of 136 NRT-related Cochrane Tobacco Addiction Group studies, substantial evidence supported NRT use in increasing the chances of successfully quitting smoking by 50 to 60% in comparison to placebo or a non-NRT control group.
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