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A user with a full genome sequence of a sample of SARS-CoV-2 can use the tool to submit that sequence, which is then compared with other genome sequences, and assigned the most likely lineage (Pango lineage). [5] Single or multiple runs are possible, and the tool can return further information regarding the known history of the assigned lineage ...
Date/Time Thumbnail Dimensions User Comment; current: 05:47, 13 September 2022: 3,469 × 3,468 (1.86 MB): MinMaj7th: updated with new lineage information: 22:51, 7 May 2022
SARS-CoV-2-CDC-23312.png SARS-CoV-2 (CDC-23311).png SARS-CoV-2 (CDC-23313).png Valued image This image has been assessed under the valued image criteria and is considered the most valued image on Commons within the scope: Illustration of a severe acute respiratory syndrome coronavirus 2 virion .
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This variant of SARS-CoV-2 has been named lineage P.1 (although it is a descendant of B.1.1.28, the name B.1.1.28.1 [67] [126] is not permitted and thus the resultant name is P.1), and has 17 unique amino acid changes, 10 of which in its spike protein, including the three concerning mutations: N501Y, E484K and K417T.
The SARS-CoV-2 Kappa variant is also known as lineage B.1.617.1 and was first detected in India in December 2020. [2] By the end of March 2021, the Kappa sub-variant accounted for more than half of the sequences being submitted from India. [ 3 ]
SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV. [105] Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus (beta-CoV lineage B). [106] [107] Coronaviruses undergo frequent recombination. [108]
Although the lineages P.1 and P.3 stem from the same lineage B.1.1.28, the department said that the impact of lineage P.3 on vaccine efficacy and transmissibility is yet to be ascertained. [ 10 ] On March 17, 2021, the United Kingdom confirmed its first two cases, where Public Health England (PHE) termed it VUI-21MAR-02.