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It is possible for a substance to be both a laxative and a cathartic. However, agents such as psyllium seed husks increase the bulk of the feces. [2] [3] Cathartics such as sorbitol, magnesium citrate, magnesium sulfate, or sodium sulfate were previously used as a form of gastrointestinal decontamination following poisoning via ingestion.
Laxatives, purgatives, or aperients are substances that loosen stools [1] and increase bowel movements. They are used to treat and prevent constipation . Laxatives vary as to how they work and the side effects they may have.
Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
In addition to pharmacological effects, rectal administration has some properties which can be advantageous for the use in medicine. Rectal administration can allow patients to remain in the home setting when the oral route is compromised.
Laxatives work in many different ways depending on what type of laxative they are. Some laxatives require a prescription, while others can be over-the-counter. There are many different types of ...
Sodium citrate saline is one of the most effective osmotic laxatives (secondary in action only to magnesium citrate). [8] Its laxative action is the result of osmotic imbalance that extracts bound water from stool and pulls it back into the large bowel. The increased water content softens the stool and stimulates the bowel to contract (move its ...
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Sorbitol is found in some dried fruits and may contribute to the laxative effects of prunes. [40] and is available for taking orally as a laxative. [41] [42] As an enema for constipation, the recommended adult dose is 120 mL of 25-30% solution, administered once. [43] Note that Sorbitol is an ingredient of the MICROLAX Enema.