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  2. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    Metolazone and a loop diuretic will synergistically enhance diuresis over the use of either agent alone. Using this combination, diuretic effects will occur at two different segments of the nephron; namely, the loop diuretic will act at the loop of Henle, and metolazone will act at the distal convoluted tubule. Metolazone is frequently ...

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart can be a useful tool, but the user must take care to correct for all relevant variables such as route of administration, cross tolerance, half-life and the bioavailability of a drug. [5] For example, the narcotic levorphanol is 4–8 times stronger than morphine, but also has a much longer half-life. Simply switching the ...

  4. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    At the same time, loop diuretics inhibit the tubuloglomerular feedback mechanism so that increase in salts at the lumen near macula densa does not trigger a response that reduces the GFR. [6] Loop diuretics also inhibit magnesium and calcium reabsorption in the thick ascending limb. Absorption of magnesium and calcium are dependent upon the ...

  5. Chlortalidone - Wikipedia

    en.wikipedia.org/wiki/Chlortalidone

    Chlortalidone, also known as chlorthalidone, is a thiazide-like diuretic drug [1] used to treat high blood pressure, swelling (such as occurs in heart failure, liver failure, and nephrotic syndrome), diabetes insipidus, and renal tubular acidosis.

  6. Calendar-based contraceptive methods - Wikipedia

    en.wikipedia.org/wiki/Calendar-based...

    These methods may be used to achieve pregnancy by timing unprotected intercourse for days identified as fertile, or to avoid pregnancy by avoiding unprotected intercourse during fertile days. The first formalized calendar-based method was developed in 1930 by John Smulders, a Catholic physician from the Netherlands .

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    mail.aol.com

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  8. Triamterene - Wikipedia

    en.wikipedia.org/wiki/Triamterene

    Triamterene directly blocks the epithelial sodium channel [4] (ENaC) on the lumen side of the kidney collecting tubule. [5]: 127 Other diuretics cause a decrease in the sodium concentration of the forming urine due to the entry of sodium into the cell via the ENaC, and the concomitant exit of potassium from the principal cell into the forming urine.

  9. Amiloride - Wikipedia

    en.wikipedia.org/wiki/Amiloride

    [1] [2] Amiloride is classified as a potassium-sparing diuretic. Amiloride is often used together with another diuretic, such as a thiazide or loop diuretic. [2] It is taken by mouth. [1] Onset of action is about two hours and it lasts for about a day. [2] Common side effects include high blood potassium, vomiting, loss of appetite, rash, and ...