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  2. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    Apixaban is recommended by the National Institute for Health and Clinical Excellence for the prevention of stroke and systemic embolism in people with non-valvular atrial fibrillation and at least one of the following risk factors: prior stroke or transient ischemic attack, age 75 years or older, diabetes, or symptomatic heart failure.

  3. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    In addition, a salt bridge between Glu-97 of thrombin and the amidine group fixed in the pyrrolidine ring of DX-9065a reduces the flexibility of the DX-9065a molecule, which now cannot rotate enough to avoid the electrostatic clash. That's why the IC 50 value for thrombin is >1000μM while the IC 50 value for FXa is 0.16μM. [22]

  4. List of herbs with known adverse effects - Wikipedia

    en.wikipedia.org/wiki/List_of_herbs_with_known...

    "rare and mild gastrointestinal upset, headaches, diarrhea, gynecomastia, paroxysmal atrial fibrillation, ventricular rupture and death in one patient" [3] Senna: Egyptian senna Senna alexandrina (Cassia senna) "abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents", [3 ...

  5. 5 foods to eat when you have diarrhea and 5 to avoid - AOL

    www.aol.com/news/5-foods-eat-diarrhea-5...

    Avoid sugary foods and drinks, even those with artificial sweeteners like stevia and aspartame, like baked goods, candy, and soda when you have diarrhea. 5. Foods that cause gas

  6. Antimotility agent - Wikipedia

    en.wikipedia.org/wiki/Antimotility_agent

    Bismuth subsalicylate (BSS) has both antibacterial and anti-secretory actions that help with diarrhea. [1] Once in the gut, BSS gets broken down into bismuth and salicylic acid. [ 1 ] Bismuth produces other bismuth salts, which blocks the binding and proliferation of bacteria in stomach mucosal cells, leading to a decrease in inflammation in ...

  7. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    The monitoring of warfarin and keeping the international normalized ratio (INR) between 2.0 and 3.0, along with avoiding over and under treatment, has driven a search for an alternative. [3] [14] A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15]

  8. Gastroenteritis - Wikipedia

    en.wikipedia.org/wiki/Gastroenteritis

    Antimotility medication has a theoretical risk of causing complications, and although clinical experience has shown this to be unlikely, [43] these drugs are discouraged in people with bloody diarrhea or diarrhea that is complicated by fever. [77] Loperamide, an opioid analogue, is commonly used for the symptomatic treatment of diarrhea. [78]

  9. Tips For Seniors Over 65 With ED - AOL

    www.aol.com/tips-seniors-over-65-ed-125700073.html

    Tips For Seniors Over 65 With ED. Nicholas Gibson. April 30, 2024 at 8:57 AM. ... While ED is commonly associated with aging, it doesn’t mean men 65 and older have to suffer from dysfunction.

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