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It is often impossible to distinguish TRALI from acute respiratory distress syndrome (ARDS). The typical presentation of TRALI is the sudden development of shortness of breath, severe hypoxemia (O 2 saturation <90% in room air), low blood pressure, and fever that develop within 6 hours after transfusion and usually resolve with supportive care within 48 to 96 hours.
TACO and transfusion-related acute lung injury (TRALI) are both complications following a transfusion, and both can result in respiratory distress. [2] TACO and TRALI are often difficult to distinguish in the acute situation. [citation needed] Assessing fluid status is key in differentiating between the two.
In a condition such as pulmonary embolism, the pulmonary blood flow is affected, thus the ventilation of the lung is adequate, however there is a perfusion defect.Gas exchange thus becomes highly inefficient leading to hypoxemia, as measured by arterial oxygenation.
Acute respiratory distress syndrome (ARDS) is a type of respiratory failure characterized by rapid onset of widespread inflammation in the lungs. [1] Symptoms include shortness of breath (dyspnea), rapid breathing (tachypnea), and bluish skin coloration (cyanosis). [1]
Silent hypoxia (also known as happy hypoxia) [115] [116] is generalised hypoxia that does not coincide with shortness of breath. [ 117 ] [ 118 ] [ 119 ] This presentation is known to be a complication of COVID-19 , [ 120 ] [ 121 ] and is also known in atypical pneumonia , [ 122 ] altitude sickness, [ 123 ] [ 124 ] [ 125 ] and rebreather ...
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Tissue hypoxia refers to low levels of oxygen in the tissues of the body and the term hypoxia is a general term for low levels of oxygen. [2] Hypoxemia is usually caused by pulmonary disease whereas tissue oxygenation requires additionally adequate circulation of blood and perfusion of tissue to meet metabolic demands.
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