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Coronary occlusion is caused by plaque inside of the blood vessels that direct oxygen rich blood to the heart. [8] Plaque is caused by fatty deposits and scar tissue that cling to the walls of coronary arteries. [9] The development of plaque takes years and leads to stenosis of the coronary arteries and progressively reduces blood flow. [8]
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]
The most common cause of a myocardial infarction is the rupture of an atherosclerotic plaque on an artery supplying heart muscle. [ 41 ] [ 72 ] Plaques can become unstable, rupture, and additionally promote the formation of a blood clot that blocks the artery; this can occur in minutes.
Plaque build-up often doesn’t cause symptoms, but it can block blood flow to vital organs like your heart. Coronary artery disease occurs when atherosclerosis affects the arteries supplying ...
The most common type is coronary artery disease, in which plaque builds up in the arteries and blocks blood flow to the heart, potentially leading to heart attacks or heart failure.
It is caused by more severe narrowing of the arteries. [9] Heart attack. A heart attack results from a sudden plaque rupture and formation of a thrombus (blood clot) that completely blocks blood flow to a portion of the heart, leading to tissue death . CAD can also result in heart failure or arrhythmias. Heart failure is caused by chronic ...
Hemorrhagic infarct, apex lower lobe, left lung Heart: Myocardial infarction (MI), commonly known as a heart attack, is an infarction of the heart, causing some heart cells to die. This is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque, which is an unstable collection ...
The most frequent cause of MI is the rupturing of an atherosclerotic plaque formed in CAD. Plaque rupture exposes the subendothelial matrix beneath the plaque, initiating thrombus formation within the vasculature. [7] The thrombus deposits on the ruptured plaque to completely block the coronary artery, halting oxygen supply to cardiomyocytes.