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It’s unclear if DHEA is safe in high doses or for long-term use. Doses above 50 to 100 milligrams a day or taking DHEA for an extended period could up your odds of serious side effects. Samara ...
Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
Levels of DHEA-S in circulation are approximately 250 to 300 times those of DHEA. [20] DHEA-S in turn can be converted back into DHEA in peripheral tissues via steroid sulfatase (STS). [54] [55] The terminal half-life of DHEA is short at only 15 to 30 minutes. [56] In contrast, the terminal half-life of DHEA-S is far longer, at 7 to 10 hours. [56]
7-Ketodehydroepiandrosterone (7-keto-DHEA, 7-oxo-DHEA), also known as 7-oxoprasterone, is a steroid prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). [ 1 ] [ 2 ] Pharmacodynamics
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Dehydroepiandrosterone (DHEA), DHEA sulfate (DHEA-S), and androstenedione may all be considered proandrogens of testosterone. [ 1 ] In the last two decades, prohormones have also been used by bodybuilders, athletes, and nonmedical users of AAS and other hormones to refer to substances that are expected to convert to active hormones in the body.
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