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Serious side effects may include psychosis, increased risk of infections, adrenal suppression, and bronchospasm. [6] Use in pregnancy is generally safe. [7] It works by decreasing inflammation and immune system activity. [6] Triamcinolone was patented in 1956 and came into medical use in 1958. [8] It is available as a generic medication. [9]
Triamcinolone acetonide is also used in veterinary medicine as an ingredient in topical ointments and in topical sprays for control of pruritus in dogs. [28] A series of injections with triamcinolone acetonide or another corticosteroid may reduce keloid size and irritation. It is used as a preinductor and/or inductor of birth in cows.
Side effects may occur from sudden discontinuation and prolonged, ... (Aclovate cream, ointment) Triamcinolone acetonide 0.025% (Aristocort A cream, Kenalog lotion)
Even low-potency topical glucocorticoids are able to cause adverse effects in children when used for prolonged periods of time. Generally, a smaller dose of topical glucocorticoid is required by children for a given condition than adults, as children have relatively smaller body surface area compared to adults.
In people with psoriasis using topical steroids it occurs in up to 5% of people after a year of use. [5] Intermittent use of topical steroids for atopic dermatitis is safe and does not cause skin thinning. [6] [7] [8] Skin atrophy can occur with both prescription and over the counter steroids creams. [9]
It is primarily used to treat atopic dermatitis , seborrheic dermatitis, contact dermatitis and psoriasis in both adults and children. It has a fairly good safety profile [1] and is available as a cream, ointment, lotion, and as a foam under the tradename Verdeso Foam. Other trade names for creams, lotions, and ointments include Tridesilon ...
There are also other side-effects, such as hypertension, dyslipidemia, hyperglycemia, peptic ulcers, lipodystrophy, moon face, liver injury and kidney injury. The immunosuppressive drugs also interact with other medicines and affect their metabolism and action.
One of the initial clinical studies into Amcinonide, conducted by Woodford & Barry, 1979, compared topical applications Amcinonide to Triamcinolone Acetonide. Specifically, 0.1% strength preparations of each compound were tested against 0.025% Synalar Gel and 0.1% Betnovate Cream using a vasoconstrictor assay to determine bioavailability and ...