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Atezolizumab, sold under the brand name Tecentriq among others, is a monoclonal antibody medication used to treat urothelial carcinoma, non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), hepatocellular carcinoma and alveolar soft part sarcoma, [9] [11] but discontinued for use in triple-negative breast cancer (TNBC). [12]
The subcutaneous injection of atezolizumab and hyaluronidase was evaluated in IMscin001 (NCT03735121), an open-label, multi-center, international, randomized trial in adults with locally advanced or metastatic non-small cell lung cancer who were not previously exposed to cancer immunotherapy and who had disease progression following treatment with platinum-based chemotherapy. [2]
Atezolizumab (Tecentriq) is a fully humanised IgG1 (immunoglobulin 1) antibody developed by Roche Genentech. In 2016, the FDA approved atezolizumab for urothelial carcinoma and non-small cell lung cancer. Avelumab (Bavencio) is a fully human IgG1 antibody developed by Merck Serono and Pfizer.
The Academy of Sciences of Albania (Albanian: Akademia e Shkencave e Shqipërisë), founded in 1972, is the most important scientific institution in Albania. [1] In the 1980s, several research institutes began at the University of Tirana were transferred to the Academy's jurisdiction. [ 2 ]
Librazhd District (Albanian: Rrethi i Librazhdit) was one of the 36 districts of Albania, which were dissolved in July 2000 and replaced by 12 newly created counties.It had a population of 72,520 in 2001, and an area of 1,102 km 2 (425 sq mi). [1]
Fletorja Zyrtare is the official government journal of the Republic of Albania.Published in a bulletin format, the journal is under the editorial oversight of the Official Publishing Center (Albanian: Qendra e Botimeve Zyrtare – QBZ) which is the only institution in the country authorized for its publication. [1]
Etrolizumab (rhuMAb Beta7) is a biopharmaceutical drug candidate being developed for the treatment of ulcerative colitis and Crohn's disease.It is a humanized monoclonal antibody against the β7 subunit of integrins α4β7 and αEβ7. [1]
The Albanians (Albanian: Shqiptarët) and their country Albania (Shqipëria) have been identified by many ethnonyms.The native endonym is Shqiptar.The name "Albanians" (Latin: Albanenses/Arbanenses) was used in medieval Greek and Latin documents that gradually entered European languages from which other similar derivative names emerged. [1]