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The pia mater is a thin fibrous tissue that is permeable to water and small solutes. [2] [3] The pia mater allows blood vessels to pass through and nourish the brain. The perivascular space between blood vessels and pia mater is proposed to be part of a pseudolymphatic system for the brain (glymphatic system).
Nervous tissue, also called neural tissue, is the main tissue component of the nervous system.The nervous system regulates and controls body functions and activity. It consists of two parts: the central nervous system (CNS) comprising the brain and spinal cord, and the peripheral nervous system (PNS) comprising the branching peripheral nerves.
The blood–brain barrier (BBB) is a highly selective semipermeable border of endothelial cells that regulates the transfer of solutes and chemicals between the circulatory system and the central nervous system, thus protecting the brain from harmful or unwanted substances in the blood. [1]
The nervous system consists of nervous tissue which, at a cellular level, is defined by the presence of a special type of cell, called the neuron. Neurons have special structures that allow them to send signals rapidly and precisely to other cells.
Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output. [9] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. [10] [11] [12]
These blood compounds are toxic to nervous tissue and precipitate neuroinflammation, edema, and eventual motor neuron death. [ 10 ] [ 12 ] [ 13 ] Multiple sclerosis (MS), a neurodegenerative, autoimmune disease that deteriorates the myelin sheath coating axons and causes permanent damage to nerves, has also been associated with capillary and ...
The autonomic nervous system influences choroid plexus CSF secretion, with activation of the sympathetic nervous system decreasing secretion and the parasympathetic nervous system increasing it. [3] Changes in the pH of the blood can affect the activity of carbonic anhydrase , and some drugs (such as furosemide , acting on the Na-K-Cl ...
Cerebral hyperaemia is a fundamental central nervous system mechanism of homeostasis that increases blood supply to neural tissue when necessary. [3] This mechanism controls oxygen and nutrient levels using vasodilation and vasoconstriction in a multidimensional process involving the many cells of the neurovascular unit, along with multiple ...