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  2. Cellular senescence - Wikipedia

    en.wikipedia.org/wiki/Cellular_senescence

    Aging of the immune system (immunosenescence) results in a diminished capacity of the immune system to remove senescent cells, thereby leading to an increase in senescent cells. [65] Chronic inflammation due to SASP from senescent cells can also reduce the capacity of the immune system to remove senescent cells. [ 66 ]

  3. Bell System - Wikipedia

    en.wikipedia.org/wiki/Bell_System

    The Fall of the Bell System A Study in Prices and Politics (1987) Watzinger, Martin, and Monika Schnitzer. "The breakup of the Bell System and its impact on US innovation." (2022). online; White, Lawrence J. "US telephone deregulation: lessons to be learned, mistakes to be avoided." Japan and the World Economy 12.2 (2000): 173-183. online}

  4. Breakup of the Bell System - Wikipedia

    en.wikipedia.org/wiki/Breakup_of_the_Bell_System

    The monopoly position of the Bell System in the U.S. was ended on January 8, 1982. AT&T Corporation proposed by in a consent decree to relinquish control of the Bell Operating Companies, which had provided local telephone service in the United States. [1]

  5. Immunosenescence - Wikipedia

    en.wikipedia.org/wiki/Immunosenescence

    Immunosenescence is the gradual deterioration of the immune system, brought on by natural age advancement. A 2020 review concluded that the adaptive immune system is affected more than the innate immune system. [1] Immunosenescence involves both the host's capacity to respond to infections and the development of long-term immune memory.

  6. Senescence - Wikipedia

    en.wikipedia.org/wiki/Senescence

    Senescence (/ s ɪ ˈ n ɛ s ə n s /) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence involves an increase in death rates or a decrease in fecundity with increasing age, at least in the later part of an organism's life cycle.

  7. Stem cell theory of aging - Wikipedia

    en.wikipedia.org/wiki/Stem_cell_theory_of_aging

    Also, some diseases related to hematopoietic system, such as aplastic anemia and complete bone marrow failure, are not especially age-dependent. Aplastic Anemia is often an adverse effect of certain medications [ 17 ] but as such it cannot really be considered as evidence against the stem cell theory of aging.

  8. Mitochondrial theory of ageing - Wikipedia

    en.wikipedia.org/wiki/Mitochondrial_theory_of_ageing

    The mitochondrial theory of ageing has two varieties: free radical and non-free radical. The first is one of the variants of the free radical theory of ageing. It was formulated by J. Miquel and colleagues in 1980 [1] and was developed in the works of Linnane and coworkers (1989). [2] The second was proposed by A. N. Lobachev in 1978. [3]

  9. Evolution of ageing - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_ageing

    The somatic mutation theory of ageing states that accumulation of mutations in somatic cells is the primary cause of aging. A comparison of somatic mutation rate across several mammal species found that the total number of accumulated mutations at the end of lifespan was roughly equal across a broad range of lifespans. [ 16 ]