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Typically, most white blood cells (WBCs) in urine are neutrophils. They are round, larger than RBCs, possess a cell nucleus , and have a granular appearance. A few white blood cells can normally be found in the urine of healthy individuals; females tend to have slightly more than males.
Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection. White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may ...
The different white blood cells are usually classified by cell lineage (myeloid cells or lymphoid cells). White blood cells are part of the body's immune system. They help the body fight infection and other diseases. Types of white blood cells are granulocytes (neutrophils, eosinophils, and basophils), and agranulocytes (monocytes, and ...
A white blood cell differential is a medical laboratory test that provides information about the types and amounts of white blood cells in a person's blood. The test, which is usually ordered as part of a complete blood count (CBC), measures the amounts of the five normal white blood cell types – neutrophils, lymphocytes, monocytes, eosinophils and basophils – as well as abnormal cell ...
Pyuria is the condition of urine containing white blood cells or pus. Defined as the presence of 6-10 or more neutrophils per high power field of unspun, voided mid-stream urine, it can be a sign of a bacterial urinary tract infection. Pyuria may be present in people with sepsis, or in older people with pneumonia.
The test for leukocyte esterase is purely indicative and should not be solely relied on for diagnosis, as it does not replace microscopic or urine culture examinations. [19] The urine test strip reaction is based on the action of leukocyte esterase in catalysing the hydrolysis of an ester of indolecarboxylic acid.
Reference ranges for urine tests are described below: Measurement Lower limit Upper limit ... White blood cells (WBCs) 0 [2] 2 [2] pH: 5 [2] 7 [2] (unitless) Protein ...
In urine cytology, collected urine is examined microscopically. One limitation, however, is the inability to definitively identify low-grade cancer cells and urine cytology is used mostly to identify high-grade tumors. [4] If the test detects atypical or cancerous cells, further tests may be recommended, such as cystoscopy and a CT scan.