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On treatment for male erectile dysfunction (ED), a review article by Tam et al. (2001) concluded: Although well-tolerated and safe, even when greatly exceeding the likely therapeutic range, it is obvious that the efficacy of [yohimbine] as monotherapy in the general ED population is likely to be modest.
[2] [3] Yohimbe bark and extract are used in manufactured dietary supplements, but there is no scientific evidence they have any effect, and yohimbine levels may vary substantially among supplement products. [2] [3] Although proposed as a potential treatment for erectile dysfunction in humans, there are concerns about its safety or effectiveness.
Anorgasmia is a type of sexual dysfunction in which a person cannot achieve orgasm despite adequate sexual stimulation. Anorgasmia is far more common in females (4.6%) [1] than in males and is especially rare in younger men. The problem is greater in women who are post-menopausal. [1] In males, it is most closely associated with delayed ...
This is a list of investigational sexual dysfunction drugs, or drugs that are currently under development for clinical treatment of sexual dysfunction but are not yet approved. Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses. This list was last comprehensively updated in June 2017.
Yohimbe bark contains both α 1 and α 2 adrenergic receptors blocking alkaloids. Phentolamine, a non-selective alpha blocker, has also been tested to treat erectile dysfunction. By reducing vasoconstriction in the penis, there appears to be increased blood flow that aids in penile erection.
Marked as VyleesiTM, it was primarily designed for both men and women in the form of an intranasal formulation, particularly for treating male erectile dysfunction. [23] However, the research was discontinued and focused on targeting female HSDD [23] in a subcutaneous injection to increase bioavailability. [3]
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