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Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, [13] to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions.
Serious side effects may include psychosis, increased risk of infections, adrenal suppression, and bronchospasm. [6] Use in pregnancy is generally safe. [7] It works by decreasing inflammation and immune system activity. [6] Triamcinolone was patented in 1956 and came into medical use in 1958. [8] It is available as a generic medication. [9]
Ocular effects: Topical steroid drops are frequently used after eye surgery but can also raise intraocular pressure (IOP) and increase the risk of glaucoma, cataract, retinopathy as well as systemic adverse effects. [14] Tachyphylaxis: The acute development of tolerance to the action of a drug after repeated doses. [15]
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones.Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism ...
Mantoux intradermal injection Intradermal needle insertion angle compared with other injection types.. The traditional procedure of ID injection known as the Mantoux procedure (as used in the Mantoux test) involves injecting at angle of administration of 5 to 15 degrees angle, almost against the skin.
The symptoms of DRESS syndrome usually begin 2 to 6 weeks but uncommonly up to 8–16 weeks after exposure to an offending drug. Symptoms generally include fever, an often itchy rash which may be morbilliform or consist mainly of macules or plaques, facial edema (i.e. swelling, which is a hallmark of the disease), enlarged and sometimes painful lymph nodes, and other symptoms due to ...
A 2020 systematic review showed greater than 50% hair regrowth in 80.9% of patients treated with 5 mg/mL triamcinolone injections. [11] A Cochrane-style systematic review published in 2019 showed 5% topical minoxidil was more than 8x more associated with >50% hair regrowth at 6 months compared to placebo. [10]
Another 2015 study reported negative effects of intra-articular corticosteroid injections at higher doses, [12] and a 2017 trial showed reduction in cartilage thickness with intra-articular triamcinolone every 12 weeks for 2 years compared to placebo. [13]