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An ingredient with a GRAS designation is exempted from the usual Federal Food, Drug, and Cosmetic Act (FFDCA) food additive tolerance requirements. [2] The concept of food additives being "generally recognized as safe" was first described in the Food Additives Amendment of 1958 , and all additives introduced after this time had to be evaluated ...
The Consumer Health Product Database is a web-based application that allows the public to search for specific products or specific chemical ingredients. It is a collection of publicly available information, mostly from product labels and Safety Data Sheets (former MSDS) provided by the product's manufacturer. [1]
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The documents published use the HL7 version 3 Structured Product Labeling (SPL) standard, [1] which is an XML format that combines the human readable text of the product label with structured data elements that describe the composition, form, packaging, and other properties of the drug products in detail according to the HL7 Reference ...
Except where stated, the list of INS numbers and associated food additives is based on the most recent publication of the Codex Alimentarius, [2] Class Names and the International Numbering System for Food Additives, first published in 1989, with revisions in 2008 and 2011. E number and American approval flags are derived from other sources.
For single-ingredient records, Seq1=01 identifies a specific active moiety. If Seq1 is higher than 01 it refers to variations of that active moiety. For multi-ingredient records, Seq1=01 identifies a combination of active moieties. If Seq1 is higher than 01 it refers to variations of one or more of the active moieties in the combination.
The LOLI Database, an abbreviation of List Of LIsts, is an international chemical regulatory database developed and maintained by ChemADVISOR, Inc. [1]. The LOLI database is one of the primary sources of information for the creation of safety data sheets and other hazard communication documents.
The Unique Ingredient Identifier (UNII) is an alphanumeric identifier linked to a substance's molecular structure or descriptive information and is generated by the Global Substance Registration System (GSRS) of the Food and Drug Administration (FDA).