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In recommended doses, the side effects of paracetamol are mild to non-existent. [87] In contrast to aspirin, it is not a blood thinner (and thus may be used in patients where bleeding is a concern), and it does not cause gastric irritation. [88]
In contrast, paracetamol is a safe and effective medication that is taken without complications by millions of people. [52] In addition, alternative pain relief medications such as aspirin are more toxic in overdose, whereas non-steroidal anti-inflammatory drugs are associated with more adverse effects following normal use. [53]
Common side effects include dizziness, sleepiness, constipation, and vomiting. [1] [3] Serious side effects include addiction, decreased rate of breathing, low blood pressure, severe allergic reactions, and liver failure. [1] Use during pregnancy may harm the fetus. [1] Use with alcohol is not recommended. [3]
N-acetylcysteine, also known as Acetylcysteine and NAC, is a medication that is used to treat paracetamol (acetaminophen) overdose and to loosen thick mucus in individuals with chronic bronchopulmonary disorders, such as pneumonia and bronchitis. [9]
The active ingredient of its original flagship product is paracetamol (known in the United States, Canada, and various other countries as acetaminophen), an analgesic and antipyretic. Like the words paracetamol and acetaminophen, the brand name Tylenol is derived from a chemical name for the compound, N-acetyl-para-aminophenol (APAP). [1]
COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis, and some of these agents substantially increase the risk of heart attack. As a result, certain COX-2 selective inhibitors—such as rofecoxib —are no longer used due to the high risk of undiagnosed vascular disease . [ 11 ]
Codeine/paracetamol, also called codeine/acetaminophen and co-codamol, is a compound analgesic, comprising codeine phosphate and paracetamol (acetaminophen). Codeine/paracetamol is used for the relief of mild to moderate pain when paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, aspirin, and naproxen) alone do not sufficiently relieve symptoms.
Possible side effects include hypersensitivity, blood problems or, above the recommended dose, pancreatitis and vomiting. [3]Taking Lemsip alongside other medicine containing paracetamol can cause an overdose, potentially resulting in serious liver and kidney damage.
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