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Acetone, butanol, and ethanol are the most common products of solventogenesis. Some species such as Clostridium beijerinckii, Clostridium puniceum and Clostridium roseum are able to further reduce acetone to isopropanol. Several species are able to produce additional solvents under various culture conditions.
The ABE fermentation via Clostridium beijerinckii or Clostridium acetobutylicum for instance is characterized by product inhibition. This means that there is a product concentration threshold that cannot be overcome, resulting in a product stream highly diluted in water. [11] Phase equilibrium diagram for 1-butanol–ethanol–water ternary mixture
Butyrate fermentation is a process that produces butyric acid via anaerobic bacteria. This process occurs commonly in clostridia which can be isolated from many anaerobic environments such as mud, fermented foods , and intestinal tracts or feces. [ 1 ]
Clostridium perfringens (gangrene, food poisoning) Clostridioides difficile (pseudomembranous colitis) Clostridium tetani ; Clostridium botulinum ; Clostridium acetobutylicum (acetone–butanol–ethanol fermentation, or ABE process) Clostridium haemolyticum; Clostridium novyi (gas gangrene, infectious necrotic hepatitis)
Clostridium acetobutylicum, ATCC 824, is a commercially valuable bacterium sometimes called the "Weizmann Organism", after Jewish Russian-born biochemist Chaim Weizmann. A senior lecturer at the University of Manchester , England , he used them in 1916 as a bio-chemical tool to produce at the same time, jointly, acetone , ethanol , and n ...
Clostridium saccharobutylicum is an indole and notably acetone, butanol and ethanol-producing bacterium, with type strain DSM 13864 T (= ATCC BAA-117 T). [ 1 ] [ 2 ] Its genome has been sequenced. [ 3 ]
Butyryl-CoA is an intermediate of the fermentation pathway found in Clostridium kluyveri. [18] [19] [20] This species can ferment acetyl-CoA and succinate into butanoate, extracting energy through the process. [19] [20] The fermentation pathway from ethanol to acetyl-CoA to butanoate is also known as ABE fermentation.
The fermentation processes to produce propanol and butanol from cellulose are fairly tricky to execute, and the Weizmann organism (Clostridium acetobutylicum) currently used to perform these conversions produces an extremely unpleasant smell, and this must be taken into consideration when designing and locating a fermentation plant.