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Acetone, butanol, and ethanol are the most common products of solventogenesis. Some species such as Clostridium beijerinckii, Clostridium puniceum and Clostridium roseum are able to further reduce acetone to isopropanol. Several species are able to produce additional solvents under various culture conditions.
The ABE fermentation via Clostridium beijerinckii or Clostridium acetobutylicum for instance is characterized by product inhibition. This means that there is a product concentration threshold that cannot be overcome, resulting in a product stream highly diluted in water. [11] Phase equilibrium diagram for 1-butanol–ethanol–water ternary mixture
Clostridium beijerinckii; Clostridium tetanomorphum; Clostridium aurantibutyricum; These bacteria begin with butyrate fermentation, as described above, but, when the pH drops below 5, they switch into butanol and acetone production to prevent further lowering of the pH. Two molecules of butanol are formed for each molecule of acetone.
Clostridium perfringens (gangrene, food poisoning) Clostridioides difficile (pseudomembranous colitis) Clostridium tetani ; Clostridium botulinum ; Clostridium acetobutylicum (acetone–butanol–ethanol fermentation, or ABE process) Clostridium haemolyticum; Clostridium novyi (gas gangrene, infectious necrotic hepatitis)
Clostridium acetobutylicum, ATCC 824, is a commercially valuable bacterium sometimes called the "Weizmann Organism", after Jewish Russian-born biochemist Chaim Weizmann. A senior lecturer at the University of Manchester , England , he used them in 1916 as a bio-chemical tool to produce at the same time, jointly, acetone , ethanol , and n ...
Microbial food cultures are live bacteria, yeasts or moulds used in food production. Microbial food cultures carry out the fermentation process in foodstuffs. Used by humans since the Neolithic period (around 10 000 years BC) [1] fermentation helps to preserve perishable foods and to improve their nutritional and organoleptic qualities (in this case, taste, sight, smell, touch).
Clostridium saccharobutylicum is an indole and notably acetone, butanol and ethanol-producing bacterium, with type strain DSM 13864 T (= ATCC BAA-117 T). [ 1 ] [ 2 ] Its genome has been sequenced. [ 3 ]
Butyryl-CoA is an intermediate of the fermentation pathway found in Clostridium kluyveri. [18] [19] [20] This species can ferment acetyl-CoA and succinate into butanoate, extracting energy through the process. [19] [20] The fermentation pathway from ethanol to acetyl-CoA to butanoate is also known as ABE fermentation.