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Hypovitaminosis D has been associated with many neurological conditions. However, an actual mechanism of action for each of the conditions has yet to be solidified. Many researchers have questioned whether the depletion of vitamin D actually causes these disorders or if vitamin D deficiency is a symptom of these disorders. [medical citation needed]
The most common causes of hypercalcemia are certain types of cancer, hyperparathyroidism, hyperthyroidism, pheochromocytoma, excessive ingestion of vitamin D, sarcoidosis, and tuberculosis. [3] Hyperparathyroidism and malignancy are the predominant causes. [14] It can also be caused by muscle cell breakdown, prolonged immobilization ...
Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
The earlier the oral cancer is diagnosed, the better the chances for full recovery. Persistent suspicious masses or ulcers on the mouth should always be examined. Diagnosis is usually made with a biopsy; treatment depends on the exact type of cancer, where it is situated, and extent of spreading.
While serum low 25-hydroxyvitamin D status has been associated with a higher risk of cancer in observational studies, [101] [102] [103] the general conclusion is that there is insufficient evidence for an effect of vitamin D supplementation on the risk of cancer, [2] [104] [105] although there is some evidence for reduction in cancer mortality.
The most common cause of osteomalacia is a deficiency of vitamin D, which is normally derived from sunlight exposure and, to a lesser extent, from the diet. [10] The most specific screening test for vitamin D deficiency in otherwise healthy individuals is a serum 25(OH)D level. [ 11 ]
Oral submucous fibrosis (OSF) is a chronic, complex, premalignant (1% transformation risk) condition of the oral cavity, characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of the submucosal tissues (the lamina propria and deeper connective tissues).
Atrophic glossitis is a non-specific finding, [16] and has a great many causes, usually related to iron-deficiency anemia, pernicious anemia, B vitamin complex deficiencies, [16] unrecognized and untreated celiac disease (which often presents without gastrointestinal symptoms), [17] [18] [19] or other factors such as xerostomia (dry mouth).
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