Search results
Results from the WOW.Com Content Network
The n-octanol-water partition coefficient, K ow is a partition coefficient for the two-phase system consisting of n-octanol and water. [1] K ow is also frequently referred to by the symbol P, especially in the English literature. It is also called n-octanol-water partition ratio. [2] [3] [4]
The partition coefficient between n-Octanol and water is known as the n-octanol-water partition coefficient, or K ow. [62] It is also frequently referred to by the symbol P, especially in the English literature. It is also known as n-octanol-water partition ratio. [63] [64] [65]
Coefficients for partition between water and solvents wet/dry solvent c e s a b v source w 1-butanol: 0.376 0.434 -0.718 -0.097 -2.350 2.682 [1]w
Bioconcentration factors can also be related to the octanol-water partition coefficient, K ow. The octanol-water partition coefficient (K ow) is correlated with the potential for a chemical to bioaccumulate in organisms; the BCF can be predicted from log K ow, via computer programs based on structure activity relationship (SAR) [7] or through ...
A calculated octanol-water partition coefficient (Clog P) that does not exceed 5; Note that all numbers are multiples of five, which is the origin of the rule's name. As with many other rules of thumb, such as Baldwin's rules for ring closure, there are many exceptions.
Thus, the freely dissolved interstitial water concentration of nonionic organic chemicals can be predicted using the K OC, the organic carbon-water partition coefficient, which is a constant for each chemical: K OC = C OC /C d. For nonionic organic contaminants, the K OC can be determined based on the octanol-water partition coefficient (K OW).
The distribution of a compound between water and octanol is used to calculate the partition coefficient, P, of that molecule (often expressed as its logarithm to the base 10, log P). Water/octanol partitioning is a relatively good approximation of the partitioning between the cytosol and lipid membranes of living systems. [5]
Where: R is the Ideal gas constant (8.314 Pa·m 3 /mol·K); T is the absolute temperature (K); H is the Henry's law constant for the target chemical (Pa/m 3 mol); K ow is the octanol-water partition coefficient for the target chemical (dimensionless ratio); P s is the vapor pressure of the target chemical (Pa); and v is the molar volume of the ...