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Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is an autosomal recessive late-onset heredodegenerative multisystem neurological disease. The symptoms include poor balance and difficulty walking. Chronic cough and difficulty swallowing may also be present.
Cerebellar ataxia is a form of ataxia originating in the cerebellum. [1] Non-progressive congenital ataxia (NPCA) is a classical presentation of cerebral ataxias. Cerebellar ataxia can occur as a result of many diseases and may present with symptoms of an inability to coordinate balance, gait, extremity and eye movements. [ 2 ]
Ataxia (from Greek α- [a negative prefix] + -τάξις [order] = "lack of order") is a neurological sign consisting of lack of voluntary coordination of muscle movements that can include gait abnormality, speech changes, and abnormalities in eye movements, that indicates dysfunction of parts of the nervous system that coordinate movement, such as the cerebellum.
Frenkel exercises are a set of exercises developed by Professor Heinrich Sebastian Frenkel [1] to treat ataxia, in particular cerebellar ataxia. [2] They are a system of exercises consisting of slow, repeated movements. They increase in difficulty over the time of the program. [3]
Dyschronometria, also called dyschronia, is a condition of cerebellar dysfunction in which an individual cannot accurately estimate the amount of time that has passed (i.e., distorted time perception). It is associated with cerebellar ataxia, [1] [2] when the cerebellum
[citation needed] A multinational clinical trial investigating N-Acetyl-L-Leucine for the treatment of a related inherited cerebellar ataxia, ataxia-telangiectasia, began in 2019. [ 42 ] IntraBio is also conducting parallel clinical trials with N-Acetyl-L-Leucine for the treatment of Niemann-Pick disease type C [ 43 ] and GM2 gangliosidosis ...
Acute cerebellar ataxia of childhood is a childhood condition characterized by an unsteady gait, most likely secondary to an autoimmune response to infection, drug induced or paraneoplastic. [1] The most common viruses causing acute cerebellar ataxia are chickenpox virus and Epstein–Barr virus , leading to a childhood form of post viral ...
Small cohort studies have shown that individuals with cerebellar disorders recover coordination and have lower SARA scores regardless of stage or severity of their ataxia before therapy when they are regularly participating in physiotherapy or exergaming over individuals who are not. These studies suggest that multidomain physical therapy, more ...
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