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Sulfasalazine metabolizes to sulfapyridine. Serum levels should be monitored every three months, and more frequently at the outset. Serum levels above 50 μg/L are associated with side effects. In rare cases, sulfasalazine can cause severe depression in young males. It can also cause oligospermia and temporary infertility.
Combinations of DMARDs are often used, because each drug in the combination can be used in a smaller dose than if it were given alone, thus reducing the risk of side effects. [citation needed] Many patients receive an NSAID and at least one DMARD, sometimes with low-dose oral glucocorticoids. If disease remission is observed, regular NSAIDs or ...
These NSAIDs, while reducing inflammation, also inhibit platelet aggregation and increase the risk of gastrointestinal ulcers and bleeds. [11] COX-2 selective inhibitors have fewer gastrointestinal side effects, but promote thrombosis, and some of these agents substantially increase the risk of heart attack.
In this episode of In Conversation, we look at some of the most important information everyone should have about perimenopause and menopause with our special guest, Dr. Kate Clancy, from the ...
Less common side effects of bicalutamide monotherapy in men include sexual dysfunction, depression, fatigue, weakness, and anemia. Bicalutamide is well tolerated and has few side effects in women. General side effects of bicalutamide that may occur in either sex include diarrhea, constipation, abdominal pain, nausea, dry skin, itching, and rash.
[20] Two regions of the sulfonamide antibiotic chemical structure are implicated in the hypersensitivity reactions associated with the class. The first is the N1 heterocyclic ring, which causes a type I hypersensitivity reaction.
As people spend more time in the bathroom with their devices, doctors share their concerns about the possible negative health effects of prolonged sitting. Don’t sit on the toilet for more than ...
Sexual side effects are the most common, Dr. Rossi says. This might include erectile dysfunction , low libido, and a decrease in sperm quality, Dr. Doshi says.
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